Catania

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7 March 2013

Celonova Biosciences

Canada

Canada

Health and Fitness

"A NanoThin surface treatment of Polyzene®-F increases the biocompatibility of the stent and does not trigger the coagulation cascade, which in turn leads to thrombosis reduction. Inflammatory response is related to the complement system (immune response) and potentially adverse effects such as myxoid tissue formation."

"The CATANIA(TM) Polyzene(R)-F surface treatment is an inorganic polymer that confers superior biocompatibility and lubricity to the substrates it coats. The Polyzene(R)-F treated surface is anti-inflammatory, promotes quick and complete vessel healing, reduces peri-operative and post-procedural platelet activation, and helps to prevent tissue reactions that lead to restenosis."

" It is contended that the surface of the Polyzene ® -F-treated stent would be haemocompatible and could promote total, rapid healing of the vessels. It thus would reduce platelet activation during and after surgery, and help to prevent inflammatory tissue reactions responsible for restenosis. "

Polymer

Nanoparticles, under 60 nm

Health applications

Surface bound particles

Dermal

Category 4 (Unsupported claim)